Investigating inner ear disorders
Our researchers are advancing knowledge in early detection, preventive strategies and treatment to alleviate inner ear conditions.
Learn more about the projects we are undertaking in this area.
Novel tools to understand balance function
Full title: From bundle to synapse: Using novel tools to understand balance function
Funded by: a Macquarie University Research Fellowship, supporting Dr Christopher Pastras
One in three individuals will experience a balance disorder in their lifetime, often originating from inner ear dysfunction.
Despite the evolutionary antiquity of the balance system, gaps persist in understanding its operation.
The primary goal is to inform the development of innovative technologies for therapeutic and diagnostic interventions.
Specific aims include:
- measuring the balance system’s dynamic response
- characterising the relationship between receptor function and morphology
- assessing neural responses from different vestibular afferent subpopulations to enhance understanding and treatment.
Dr Pastras and the research team are working with Cochlear to better understand activation of the vestibular system for development of translational devices, such as vestibular implants.
- Dr Christopher Pastras
- Professor David McAlpine
- Professor Mohsen Asadnia
- Associate Professor David Inglis
- Honorary Professor Ian Curthoys (Macquarie University, University of Sydney)
- Dr Daniel Brown (Curtin University)
- Professor Richard Rabbitt (University of Utah)
Our research partners:
- Cochlear Limited
Contact: christopher.pastras@mq.edu.au
Ménière’s disease research
Funded by: Sydney Ménière’s Support Group: Ménière’s Disease Support
Ménière’s disease, an inner ear disorder named after its French discoverer, causes:
- vertigo
- tinnitus
- hearing loss
- a feeling of fullness or congestion.
Its origin, marked by abnormal fluid accumulation in the inner ear, remains unknown.
Researchers plan a multidisciplinary approach to unravel its mysteries, collaborating with experts to:
- advance understanding
- enhance early detection
- develop preventive strategies and treatments.
- Dr Christopher Pastras
- Professor David McAlpine
- Professor Mohsen Asadnia
- Professor Payal Mukherjee (Macquarie University, University of Sydney)
- Professor Jose Antonio Lopez Escamez (University of Sydney)
- Dr Daniel Brown (Curtin University)
- Professor William Gibson (NextSense)
- Dr Celene McNeill (Healthy Hearing and Balance Care)
Contact: christopher.pastras@mq.edu.au
Meet our researchers and partners at Ménière’s Research Australia.