Bibliography: Professor S Bruce Dowton

Original Articles

  1. Dowton SB, Lawrence JR, Barratt LJ, Goodhand G. Sex difference in human erythrocyte potassium levels. Aust J Exp Biol & Med 1981; 59(3):369
  2. Jaworski RC, Dowton B, Grant A, Gibson M, Chapuis PH, Pheils MT. Colorectal carcinoma and lymphoma. Aust & NZ J Surg 1982; 52(1):37
  3. Sargent RK, Rossing TH, Dowton SB, Breyer MD, Levine L, Weinstein L. Diphtheria immunity in Massachusetts: a study of three urban populations. Am J Med Sci 1984; 287:37
  4. Dowton SB, Beardsley D, Jamison D, Blattner S, Li FP. Studies of a familial platelet disorder. Blood 1985; 65(3):557
  5. Dowton SB, Woods DE, Mantzouranis EC, Colten HR. Syrian hamster female protein: analysis of female protein primary structure and gene expression. Science 1985; 228:1206
  6. Mantzouranis EC, Dowton SB, Whitehead AS, Edge MD, Bruns GAP, Colten HR. Human serum amyloid P component – cDNA isolation, complete sequence of pre-serum amyloid component and localization of the gene to chromosome 1. J Biol Chem 1985; 260:7752
  7. Grand MG, Kaine J, Fulling K, Atkinson J, Dowton SB, Farber M, Craver J, Rice K. Cerebroretinal vasculopathy: A new hereditary syndrome. Ophthalmology 1988; 95:649
  8. Webb CF, Tucker PW, Dowton SB. Expression and sequence analyses serum amyloid A in the Syrian hamster. Biochemistry 1989; 28:4785-4790
  9. Dowton SB, Waggoner DJ. Armenian hamster female protein (serum amyloid P component): Comparison with the sex-regulated homologue in Syrian hamster. J Immunol 1989; 143:3776-3780
  10. Marhaug G, Husby G, Dowton SB. Mink serum Amyloid A protein – Expression and primary structure based on cDNA sequences. J Biol Chem 1990; 265:10049-10054
  11. Dowton SB, McGrewSD. Rat serum amyloid P component – analysis of cDNA sequence and gene expression. Biochem J, 1990; 270:553-556
  12. Craft S, Gourovitch MD, Dowton SB, Swanson JM, Bonforte S. Lateralized deficits in visual attention in males with developmental dopamine depletion. Neuropsychologia 1992; 30(4):341
  13. Dowton SB, Waggoner DJ, Mandl KD. Developmental regulation of expression of C-reactive protein and serum amyloid A in Syrian hamsters. Pediatr Res 1991; 30:444-449
  14. Dowton SB, Holden SN. C-reactive protein (CRP) of the Syrian Hamster. Biochemistry 1991; 30:9531-9538, 1991.
  15. Dowton SB, Peters SN, Jestus JJ. Regulation of serum amyloid A gene expression in Syrian hamsters by cytokines. Inflammation 1991; 15:391-397
  16. Rygg M, Marhaug G, Husby G, Dowton SB. Rabbit serum amyloid protein A: expression and primary structure deduced from cDNA sequences. Scand J Immunol 1991; 34:727-734
  17. Rudnick CM, Dowton SB. Serum amyloid P component of the Armenian hamster: Gene structure and comparison with structure and expression of the SAP gene from Syrian hamster. Scand J Immunol 1993; 38:445-450
  18. Rudnick CM, Dowton SB. Serum amyloid P (female protein) of the Syrian hamster: Gene structure and expression. J Biol Chem 1993; 268:21760-21769
  19. Husby G, Marhaug G, Dowton SB, Sletten K, Sipe JD. Serum amyloid A (SAA): biochemistry, genetics and the pathogenesis of AA amyloidosis. Int J Exp Clin Invest 1994; 1:119-137
  20. Wells SA Jr, Chi DD, Toshima K, Dehner LP, Coffin CM, Dowton SB, Ivanovich JL, DeBenedetti MK, Moley JF, Donis-Keller H. Predictive DNA testing and prophylactic thyroidectomy in patients at risk for multiple endocrine neoplasia type 2A. Annals Surg 1994; 220:237-50
  21. Gourovitch ML, Craft S, Dowton SB, Ambrose P, Sparta S. Interhemispheric transfer in children with early-treated phenylketonuria. J Clin Exp Neuropsychol 1994; 16:393-404
  22. Johnson MC, Strauss AW, Dowton SB, Spray TL, Huddleston CB, Wood MK, Slaugh RA, Watson MS. Deletion within chromosome 22 is common in patients with absent pulmonary valve syndrome. Am J Cardiol 1995; 76:66-69
  23. Hing AV, Helms C, Slaugh, Burgess A, Wang JC, Herman T, Dowton SB, Donis-Keller H. Linkage of preaxial polydactyly type II to 7q36. Am J Med Genet 1995; 58:128-135
  24. Ho CY, Otterud B, Legare RD, Varvil T, Saxena R, DeHart DB, Kohler SE, Aster JC, Dowton SB, Li FP, Leppert M, Gilliland DG. Linkage of a familial platelet disorder with a propensity to develop myeloid malignancies to human chromosome 21q22.1-22.2. Blood 1996; 87:5218- 5244
  25. Witt PD, Myckatyn T, Marsh JL, Marty-Grames L, Dowton SB. Need for velopharyngeal management following palatoplasty: an outcome analysis of syndromic and non-syndromic patients with Robin sequence. Plast Reconstr Surg 1997; 99(6):1522-1529
  26. Marhaug G, Hackett B, Dowton SB. Serum amyloid A gene expression in rabbit, mink, and mouse. Clin Exp Immunol 1997; 107(2):425-434
  27. McNeil HP, Hughes CS, Toohey SM, Dowton SB: An Innovative Outcomes-based Medical Education Program Built on Adult Learning Principles Medical Teacher 2006; 28(6):527 – 534
  28. Macneill P and Dowton SB. Declarations made by graduating medical students in Australian  and New Zealand medical schools. Medical J Australia 2000; 176(3):123-125
  29. Macneill PU, May AN, Dowton SB. An opportunity to reinforce ethical values: declarations  made by graduating medical students in Australia and New Zealand. Internal Med J (in press)

Reviews, Chapters and Editorials

  1. Dowton SB, Colten HR. Sites and regulation of biosynthesis of SAA. In: Marrink J, Rijswijk MH, editors. Amyloidosis. Dordrecht: Martinus Nijhoff, 1986, pp 107-113
  2. Dowton SB, McGrew SD. Isolation of cDNA clones and expression analyses for rat serum amyloid P (SAP) component. In Natvig JB, Forre O, Husby G, Husebekk S, Skogen B, Sletten K, Westermark P, editors. Amyloidosis., Doortrecht: Kluwer Academic Publishers, 1990. p. 283- 287.
  3. Dowton SB, Peters CN, Morrissey J, Rudnik C. Differential regulation of SAP gene expression in Syrian and Armenian hamsters. In Natvig JB, Forre O, Husby G, Husebekk S, Skogen B, Sletten K, Westermark P, editors. Amyloidosis., Doortrecht: Kluwer Academic Publishers, 1990. p. 280-283.
  4. Rygg M, Hubsy G, Dowton B, Marhaug G. Primary structure of two rabbit serum amyloid A proteins (SAA) based on cDNA sequence. In Natvig JB, Forre O, Husby G, Husebekk S, Skogen B, Sletten K, Westermark P, editors. Amyloidosis., Doortrecht: Kluwer Academic Publishers, 1990. p. 40-43.
  5. Marhaug G, Husby G, Nordstoga K, Dowton SB. Mink serum amyloid A protein – expression and primary structure of amyloidogenic and non-amyloidogenic isotypes. In Natvig JB, Forre O, Husby G, Husebekk S, Skogen B, Sletten K, Westermark P, editors. Amyloidosis., Doortrecht: Kluwer Academic Publishers, 1990. p. 36-39.
  6. Marhaug G, Dowton SB. Serum amyloid A: An acute phase apolipoprotein and precursor of AA amyloid. In Husby G, editors, Bailliere’s Clinical Rheumatology Vol 8, No 3. London, United Kingdom, 1994, p 553-573
  7. Colten HR, Dowton SB. Regulation of complement gene expression. Bioch Soc Symp 1986; 51:37-46
  8. Dowton, Colten HR. Acute Phase Reactants in Inflammation and Infection. Sem in Hematol 1988; 25(2):84-90
  9. Dowton SB, Slaugh RA. Diagnosis of human heritable diseases: laboratory approaches and outcomes. Clin Chem 1995; 41:785-794
  10. Schnase JL, Cunnius E, Kelley L, Johnson DB, Ashkar JC, Wells P, Frisse ME, Dowton SB. The StudySpace project: collaborative hypermedia in medical education. Communications of the ACM (Special Issue on Applications of Hypermedia) 1995; 38(8):72-73
  11. Larkins R, Leeder S, Freewin D, Brooks P, Landau L, Saunders N, Dowton B, Carmichael A: A sea change in Australian medical education. Med J Aust 1998; 169:653-8
  12. Coiera E, Dowton SB. Reinventing ourselves. Medical J Australia 2000; 173(7):343-4
  13. Dowton SB, Brown D. Training our Future Rural Medical Workforce. Medical J Australia 
2004; 180(12):652
  14. Dowton SB: Leadership in Medicine – Where are the Leaders? Medical J Australia 2004; 
  15. Dowton SB, StokesML, Rawstron EJ, Pogson PR, Brown MA. Postgraduate Medical Education  – Rethinking and Integrating a Complex Landscape. Medical J Australia 2005; 182(4):177- 
  16. Dowton SB: Imperatives in medical education and training in response to demands for a  sustainable workforce. Medical J Australia 2005; 183(11/12):595-598

Clinical Communications

  1. Linnell JC, Miranda B, Bhatt H, Dowton SB, Levy HL. Abnormal cobalamin metabolism in a megaloblastic child with homocystinuria and methylmalonic aciduria. J Inherit Metab Dis 1983; 6(suppl)2:137
  2. Robb R, Dowton SB, Fulton AB, Levy HL. Retinal degeneration in vitamin B12 disorder associated with methylmalonic aciduria and sulfur amino acid abnormalities. Am J Ophthalmol 1984; 97:691-696
  3. Tiller GE, Watson MS, Duncan LM, Dowton SB: Congenital heart defect in a patient with deletion of the long arm of chromosome 7. Amer J Med Genet 1988; 29:283
  4. Lueder GT, Fitz-James A, Dowton SB. Congenital microgastria and hypoplastic upper limb anomalies. Am J Med Genet 1989; 32:368-370
  5. Watson MS, Dowton SB, Rohrbaugh J: Case of direct insertion within a chromosme 3 leading to a chromosome 3p duplication in an offspring. Am J Med Genet 1990; 36:172-174
  6. Raisher BD, Dowton SB, Grant JW. Brief clinical report: Father and two children with total anomalous pulmonary venous connection. Am J Med Genet 1991; 40:105-106
  7. Demmer LA, Wippold FJ, Dowton SB. Periventricular white matter cystic lesions in Lowe (oculocerebrorenal) syndrome: a new MR finding. Pediatr Radiol 1992; 22:76-77
  8. Hing AV, Torack R, Dowton SB: A lethal syndrome resembling branchio-oculo-facial syndrome. Clin Genet 1992; 41:74-78
  9. Herman TE, Mendelsohn NJ, Dowton SB. Microcephalic osteodysplastic primordial dwarfism, type II. Pediatr Radiol 1992; 21:602-604
  10. Herman TE, Mendelsohn NJ, Dowton SB, McAlister WH: Microcephhalic osteodysplastic primordial dwarfism, type II. Report of a case with characteristic skeletal features. Comment in Pediatr Radiol 1992; 22(6):476
  11. Herman TE, Sweetser DA, McAlister WH, Dowton SB: Schinzel-Giedion syndrome and congenital megacalyces. Pediatr Radiol 1993; 23(2):111-112
  12. Herman TE, Siegel MJ, Lee BCP, Dowton SB. Smith-Lemli-Opitz syndrome type II: report of a case with additional radiographic findings. Pediatr Radiol 1993; 23(1):37-40
  13. Hing A, Dowton SB. Aase syndrome: Novel radiographic findings. Am J Med Genet 1993; 45:413-415
  14. Hing A, Corteville J, Foglia RP, Bliss DP, Donis-Keller H, Dowton SB. Fetus in fetu: molecular analysis of a fetiform mass. Am J Med Genet 1993; 47:333-341
  15. Steiner RD, Sweetser DA, Rohrbaugh JR, Dowton SB, Toone JR, Applegarth DA. Nonketotic hyperglycinemia: atypical clinical and biochemical manifestations. J Pediatr 1996; 128:243- 246
  16. Demmer LA, Kim JA, Dowton SB, deMartinville B. A novel nonsense mutation in the exon containing the putative ornithine binding domain of the OTC enzyme in a female. Hum Mutat 1996; 7:279
  17. Schiro JR, Mallory SB, Demmer L, Dowton SB, Luke MC. Grouped papules in Hurler/Scheie syndrome (MPS I H/S). J Am Acad Dermatol 1996; 35:868-870
  18. Dowton SB, Pincott S, Demmer L: Respiratory Complications of Ehlers-Danlos Syndrome Type IV. Clin Genet 1996; 50(6):510-514
  19. Dowton SB, Hing AV, Sheen-Kaniecki V, Watson MS: Chromosome 18q22.2→qter deletion and a congenital anomaly syndrome with multiple vertebral segmentation defects. J Med Genet 1997; 34(5):414-417
  20. Ciske DJ, Waggoner DJ, Dowton SB: Unique cardiac and cerebral anomalies with chondrodysplasia punctata. Am J Med Genet 1998; 75(1):59-61 1998
  21. Waggoner DJ, Ueda K, Mantia C, Dowton SB: Methylmalonic aciduria (cblF): Case report and response to therapy. Am J Med Genet 1998; 79:373-375
  22. Waggoner DJ, Ciske DJ, Dowton SB, Watson MS. Deletion of 1q in a patient with acrofacial dysostosis. Am J Med Genet 1999; 82:301-304
  23. Waggoner DJ, Chow CK, Dowton SB, Watson MS. Partial monosomy of distal 10q: three cases and a review. Am J Med Genet 1999; 86(1):1-5
  24. Piersall LD, Dowton SB, McAlister WH, Waggoner DJ. Vertebral anomalies in a new family with ODED syndrome. Clinical Genet. 2000; 57:444-448

Letters to the Editor

  1. Dowton SB. Familial polyposis coli associated with familial meningiomas. Med J Aust 1980; 67(12):615.
  2. Wippold FJ, Dowton SB. Lesions in oculocerebrorenal syndrome: Letter to the editor. Am J Neuroradiology 1994; 15:1797


  1. Structure and Regulation of Expression of Genes Encoding Pentraxin and Amyloid Proteins“, examined for the degree of Doctor of Medicine – University of Sydney submitted 1993; awarded January 1994

Non Print Materials

  1. Dowton SB, Slaugh RA, Cunnius E, Kelley L: Medical Genetics – a set of instructional materials designed for use by medical students, pediatric residents and genetics fellows in Lotus Notes with gated accessibility via the internet using Lotus Domino. 1996


  1. SB Dowton, JC Linnell, FC Ledley, HL Levy: Plasma and RBC cobalamins in B12 defect disorder. Society for Pediatric Research 1982. Ped Res 16:257A.
  2. JC Linnell, B Miranda, HR Bhatt, SB Dowton, HL Levy: Abnormal cobalamin metabolism in a megaloblastic child with homocystinuria, cystathioninuria and methylmalonic aciduria. Society for the Study of Inborn Errors of Metabolism, 20th Annual Symposium, Manchester University, September 7-10, 1982.
  3. M Rygg, G Husby, SB Dowton, G Marhaug: High molecular weight serum amyloid A-like proteins in man, mink and rabbit. 12th European Congress of Rheumatology, June 30 – July 6th, 1991, Budapest, Hungary.
  4. KK Norton, I Silos-Santiago, RT Geist, SB Dowton, JL Rutkowski, DH Gutmann: Lack of NF1 gene expression in a sporadic schwannoma from a patient without neurofibromatosis. 1994 Annual Meeting of the American Society of Human Genetics.
  5. JA Petros, SB Dowton, WJ Catalona: Investigation of retinoblastoma transcripts in primary prostatic adenocarcinoma. J Urol 145:293A abstract 324, 1991.
  6. SB Dowton & IM Eisenbruch:– The Role of a University in Leading Change in Gaining Dividends from Diversity. National Conference of Productive Diversity Partnerships Program. November 2000, Melbourne
  7. HP McNeil, CS Hughes, SM Toohey, SB Dowton: An Innovative Outcome-Based Integrated Medical Education Program that encompasses Life Long Learning Capabilities. Asia-Pacific Medical Education Conference 2003.
  8. SB Dowton: Spirals of Success in Preparing New Professionals – a Complex and Uncertain Future. Royal Australasian College of Surgeons Annual Congress, Melbourne, 2004. ANZ Journal of Surgery 74 (Suppl):A116
  9. SB Dowton: Is the Sky Falling? – Teaching Anatomy in Medical Schools. Royal Australasian College of Surgeons Annual Congress, Melbourne, 2004.